γ-Aminobutyric acid elevates cytosolic Ca in bovine chromaffin cells
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چکیده
منابع مشابه
GATMD: γ-Aminobutyric Acid Transporter Mutagenesis Database
Since the cloning of the first γ-aminobutyric acid (GABA) transporter (GAT1; SLC6A1) from rat brain in 1990, more than 50 published studies have provided structure-function information on investigator-designed rat and mouse GAT1 mutants. To date, more than 200 of 599 GAT1 residues have been subjected to mutagenesis experiments by substitution with different amino acids, and the resulting transp...
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et al., 1996b). Activation of Nand P/Q-type channels Summary in these cells is effectively slowed down by ATP and opioids (Gandı́a et al., 1993; Albillos et al., 1996a) that In bovine chromaffin cells, the Ca21 channels involved are coreleased with catecholamines during exocytosis in exocytosis are effectively inhibited by ATP and opi(Viveros et al., 1979; Winkler et al., 1980). The action is oi...
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Alterations in the cytosolic pool directly affect neurotransmitter synthesis and release and are suggested to be key factors in various neurodegenerative disorders. Although this cytosolic pool is the most metabolically active, it is miniscule compared with the amount of vesicular transmitter and has never been quantified separately. Here, we introduce intracellular patch electrochemistry (IPE)...
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Social anxiety disorder (SAD) is the one of the most common anxiety disorders. Despite its high prevalence, the disorder is still considerably undiagnosed and untreated. The disease places a massive burden on patient’s lives, affecting not only their social interactions but also their educational and professional activities, thereby constituting a severe disability. γ-aminobutyric acid (GABA) s...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 1989
ISSN: 0304-3940
DOI: 10.1016/0304-3940(89)90333-9